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  • Meclizine (brand names Antivert®, Dramamine® Less Drowsy Formula, Bonine®, Bonamine®, Postafen®, Univert®) is an antihistamine used off label to prevent and treat motion sickness and vomiting associated with it, in cats, dogs, and other small mammals. The most common side effect is sedation and sleepiness.

  • For most cats, a visit to the veterinarian is an overwhelming experience. If your cat’s veterinary appointment is for a routine wellness examination, your veterinarian may prescribe a sedative or antianxiety medication. Natural medicines, also known as complementary therapies, cover a wide range of products including herbs, nutraceuticals, supplements, and homeopathic remedies and may be beneficial in treating your anxious cat. Products such as Feliway® and Rescue Remedy® are examples of natural therapies that may be helpful in reducing your cat’s stress. One of the most important ways to decrease your cat’s anxiety level is to remain calm and relaxed during the visit as this will help reassure your cat that she is safe.

  • Medicinal mushrooms are given by mouth and are used over the counter (and under veterinary supervision) to supplement the treatment of cancer and other conditions. Give as directed by your veterinarian. Side effects may include stomach upset, diarrhea, dizziness, and skin rash. Do not use in pets that are allergic to mushrooms, and use cautiously in pets that are pregnant, nursing, or have diabetes, clotting disorders, low blood pressure, immune-mediated disorders, liver problems, or kidney disease. If a negative reaction occurs, please call your veterinary office.

  • Medroxyprogesterone acetate is given by mouth or injection and is used off label to treat reproductive conditions, sexual behaviors, and certain types of dwarfism and alopecia. Give this medication as directed by your veterinarian. Common side effects include increased appetite, increased thirst, weight gain, sleepiness, or changes in personality. Do not use in pets that are allergic to it, pets with diabetes or uterine bleeding, or prior to puberty, during pregnancy, 1-2 months after a heat cycle, or to treat false-pregnancy. If a negative reaction occurs, please call your veterinary office.

  • If the nerves to the colon do not function normally, the muscles of the colonic wall will not contract properly. The muscles then become stretched and the colon enlarges in diameter. Rather than being pushed into the rectum in a normal manner, fecal material accumulates in the distended colon, resulting in severe constipation called obstipation. This massive enlargement of the colon and the resulting constipation is called megacolon. Megacolon is often treatable using a medical approach but some cases require surgical intervention called subtotal colectomy.

  • Megaesophagus is a disorder in which the esophagus dilates and loses motility. When esophageal motility is decreased or absent, food and liquid accumulate in the esophagus and have difficulty getting into the stomach. Regurgitation is the most common sign of megaesophagus. Weight loss or failure to gain weight, as well as aspiration pneumonia, are also common signs. Treatment is focused on managing the symptoms.

  • Megestrol acetate is given by mouth in the form of a tablet or liquid and is used in dogs or off label in cats to postpone the heat cycle or to treat false pregnancy. It can also be used off label in male dogs to treat prostatic hypertrophy. It should not be used in pregnant pets or pets with uterine disease, diabetes, or breast tumors.

  • Melanomas are cancerous growths of the cells responsible for pigmentation of the skin. They can develop anywhere on the body but those on the toes carry the highest chance for malignancy. They may be painful and you may notice your pet licking at the affected area. Surgery is often the treatment of choice and may be followed up with radiation or chemotherapy.

  • Melatonin is given by mouth or as an implant under the skin and is used to treat sleep and behavior disorders, adrenal disease, and non-allergic hair loss, to suppress the heat cycle, and to improve breeding rates. Give as directed. Side effects are not common but may include sleepiness. Do not use in pets that are allergic to it. If a negative reaction occurs, please call your veterinary office.

  • Melioidosis is a bacterial infection that is typically associated with tropical regions. The bacteria that causes melioidosis, Burkholderia pseudomallei, is usually found in soil and water. The clinical signs of this condition, along with transmission, diagnosis, treatment, and prognosis, are outlined in this handout.

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