Educational Articles
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Lente (porcine zinc) insulin (brand names Vetsulin®, Vetpen®) is an injectable medication approved for use in cats and dogs with diabetes mellitus. It is used to lower blood sugar levels and for long-term maintenance therapy of diabetes mellitus. This medication may be used "off label" or "extra label" in ferrets. Monitor closely for signs of low blood sugar (weakness, lack of energy, lethargy, stumbling or difficulty walking, behavior changes, muscle twitching, seizures, and/or unresponsiveness).
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NPH (Neutral Protamine Hagedron) insulin is an injectable medication used in cats, dogs, birds, ferrets, and horses with diabetes mellitus. It is used to lower blood sugar levels and for long-term maintenance therapy of diabetes mellitus. Monitor closely for signs of low blood sugar (weakness, lack of energy, lethargy, stumbling or difficulty walking, behavior changes, muscle twitching, seizures, and/or unresponsiveness).
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Protamine zinc (PZI) insulin (brand name Prozinc®) is an injectable medication approved for use in cats and dogs with diabetes mellitus. It is used to lower blood sugar levels and for long-term maintenance therapy of diabetes mellitus. This medication may be used “off label” or “extra label” in other species. Monitor closely for signs of low blood sugar (weakness, lack of energy, lethargy, stumbling or difficulty walking, behavior changes, muscle twitching, seizures, and/or unresponsiveness).
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Interferon alfa is given by mouth or injection and is used off label to treat certain viral diseases in dogs and cats. Give as directed by your veterinarian. Side effects are uncommon but may include vomiting or decreased appetite. Do not use in pets that are allergic to it or that are receiving immediate vaccination. If a negative reaction occurs, please call your veterinary office.
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Isoflupredone combinations topical are combination medications containing isoflupredone (a corticosteroid) and other medications. Isoflupredone may be compounded with an antibiotic, a local anesthetic, or other medications to treat surface skin conditions where use of a steroid combination product is indicated. Its use may off label (extra label) depending on the species, condition(s) being treated, and formulation. Isoflupredone combinations topical come in powder and ointment forms, often specially compounded.
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Itraconazole is given by mouth in the form of a capsule, tablet, or liquid to treat fungal infections in cats and for off-label treatment in dogs and small mammals. The most common side effects are anorexia, vomiting, liver toxicity, skin lesions, or limb and vessel swelling. It should not be used in pets with liver disease or low stomach acid production, and used with caution in pregnant, lactating, or pets with heart disease.
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Ivermectin is most used as a heartworm preventive in dogs and cats. It is also used off label for treating a variety of internal and external parasites. Ivermectin may be combined with other deworming medications. Ivermectin is available as tablets, chewable tablets, a topical liquid (for ear mite treatments), and an injectable that your veterinarian will administer.
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This handout outlines the use of disease-modifying osteoarthritis drugs (DMOADs) in cats, specifically the use of polysulfated glycosaminoglycans (PSGAGs). The rationale for their use, potential side effects, and treatment expectations are explained.
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Kaolin/pectin is given by mouth and is used off label to treat diarrhea and certain toxicities. Use as directed by your veterinarian. Side effects are uncommon, but constipation is possible (rarely). Do not use in pets that are allergic to it, or to control severe diarrhea or diarrhea that is caused by an infection. Do not use the combination product that includes bismuth subsalicylate in cats. If a negative reaction occurs, please call your veterinary office.
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Ketoconazole is an antifungal given by mouth in the form of a tablet, used off label to treat fungal infections in dogs, cats, small mammals, and reptiles. The most common side effects are vomiting, diarrhea, lack of appetite, and weight loss. Do not use in pets that are allergic to it and use extreme caution when using in cats or pregnant pets.
