Educational Articles

Small Mammals

  • Insulin glargine is an injectable medication used in cats, dogs, ferrets, guinea pigs, and horses with diabetes mellitus. It is used to lower blood sugar levels and for long-term maintenance therapy of diabetes mellitus. Monitor closely for signs of low blood sugar (weakness, lack of energy, lethargy, stumbling or difficulty walking, behavior changes, muscle twitching, seizures, and/or unresponsive).

  • An insulinoma is a cancerous condition involving the beta cells of the pancreas. Beta cells are the cells that produce insulin. Clinical signs may include pawing at the mouth, weight loss, tremors, collapse, abnormal behavior, depression, lethargy, and confusion. Treatment can be medical, surgical, or both with proper dietary management.

  • Itraconazole is given by mouth in the form of a capsule, tablet, or liquid to treat fungal infections in cats and for off-label treatment in dogs and small mammals. The most common side effects are anorexia, vomiting, liver toxicity, skin lesions, or limb and vessel swelling. It should not be used in pets with liver disease or low stomach acid production, and used with caution in pregnant, lactating, or pets with heart disease.

  • Kaolin/pectin is given by mouth and is used off label to treat diarrhea and certain toxicities. Use as directed by your veterinarian. Side effects are uncommon, but constipation is possible (rarely). Do not use in pets that are allergic to it, or to control severe diarrhea or diarrhea that is caused by an infection. Do not use the combination product that includes bismuth subsalicylate in cats. If a negative reaction occurs, please call your veterinary office.

  • Ketoconazole is an antifungal given by mouth in the form of a tablet, used off label to treat fungal infections in dogs, cats, small mammals, and reptiles. The most common side effects are vomiting, diarrhea, lack of appetite, and weight loss. Do not use in pets that are allergic to it and use extreme caution when using in cats or pregnant pets.

  • Ketoprofen is given by mouth in the form of a capsule or tablet to treat pain and inflammation in dogs and horses. It’s use in animals is off label. Do not use this medication in pets that are allergic to it, or in pets concurrently using corticosteroids or other NSAIDs. If a negative reaction occurs, call your veterinary office.

  • Lactated Ringer’s solution (also known as LRS, Ringer’s Lactate) is a fluid and electrolyte (salts) replacement solution used to correct fluid and electrolyte imbalances in cats, dogs, birds, pocket pets (small mammals), and other animals. Lactated Ringer’s solution comes in injectable form, usually given subcutaneously for at home administration.

  • Leuprolide is given by injection and is used off label in ferrets and birds to treat reproductive and adrenal problems. Give as directed. Side effects in ferrets may include pain at the injection site, breathing difficulties, and sleepiness. Do not use in pets that are allergic to it or other gonadotropin-releasing hormones, and do not use in pregnant or nursing pets. If a negative reaction occurs, please call the veterinary office.

  • Lincomycin is given by mouth or injection and is used on and off label to treat certain bacterial infections. Give as directed by your veterinarian. Common side effects include vomiting, diarrhea, or drooling. Do not use in pets that are allergic to it or similar drugs, in pets with a candida fungal infection, very young pets, or in rabbits, hamsters, guinea pigs, or horses. If a negative reaction occurs, please call the veterinary office.

  • Loperamide is given by mouth and is used off label to treat signs of diarrhea. Give as directed by your veterinarian. Common side effects include constipation, bloat, and sleepiness. Do not use in pets that are allergic to it, that have diarrhea due to an infection or a toxin, or that are positive for the MDR1 gene. If a negative reaction occurs, please call your veterinary office.

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